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Cholic acid

Cholic acid - Wikipedi

Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance.Salts of cholic acid are called cholates.Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol Orally administered cholic acid is subject to the same metabolic pathway as endogenous cholic acid. Cholic acid is absorbed by passive diffusion along the length of the gastrointestinal tract. Once absorbed, cholic acid enters into the body's bile acid pool and undergoes enterohepatic circulation mainly in conjugated forms Cholic acid side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Call your doctor at once if you have: blood in your stools, changes in your bowel habits (such as diarrhea or constipation);. pain or burning when you urinate; o Cholic Acids Cholsyror Svensk definition. En familj inom gallsyrorna hos människan, omfattande 3-alfa,7-alfa,12-alfa-trihydroxi-5-beta-kolansyrorna och vanligen bundna till glycin eller taurin. De verkar som lösningsmedel för fetter, så att d esa kan absorberas i tarmen Cholic acid, a major primary bile acid, which plays an important role in lipolysis and cholesterol catabolism, showed an increased trend in our study. Previous study reported that bile acids served many important physiological functions, including cholesterol homeostasis,.

Cholic acid C24H40O5 - PubChe

Cholic acid Uses, Side Effects & Warnings - Drugs

  1. Cholic acid glucuronide | C30H48O11 | CID 21252309 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological.
  2. Cholic acid, a primary bile acid, enhances bile flow and provides the physiologic feedback inhibition of bile acid synthesis to maintain bile acid homeostasis. Absorption. Absorbed by passive diffusion along the gastrointestinal tract. Patients with concomitant familial hypertriglyceridemia may have poor absorption
  3. Cholic acid is manufactured at NZP from bovine bile (also known as cattle bile or ox bile) at NZP in large quantities. Bile is a by-product sourced from government veterinarian-supervised abattoirs. Ovine bile can also be used as it is of a very similar composition. In nature, cholic acid is produced in the liver from cholesterol
  4. Display Name: Cholic acid EC Number: 201-337-8 EC Name: Cholic acid CAS Number: 81-25-4 Molecular formula: C24H40O5 IUPAC Name: (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
  5. IUPAC Standard InChIKey: ZSNMWSXGJNFSAV-HAVJKBGOSA-N CAS Registry Number: 81-25-4 Chemical structure: This structure is also available as a 2d Mol file; Stereoisomers: 3Beta,7beta,12beta-trihydroxy-5beta-cholan-24-oic acid
  6. A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion

Cholic acid (Chem.) a complex organic acid found as a natural constituent of taurocholic and glycocholic acids in the bile, and extracted as a resinous substance, convertible under the influence of ether into white crystals Cholic acid is the predominant primary bile acid in humans, which can be used to provide a source of bile acid in patients with inborn deficiencies in bile acid synthesis. Indications and dose. Inborn errors of primary bile acid synthesis (initiated by a specialist) By mouth. For Adult

Cholsyror Svensk MeS

  1. cholic acid translation in English-Swedish dictionary. Showing page 1. Found 49 sentences matching phrase cholic acid.Found in 7 ms
  2. cholic acid översättning i ordboken engelska - svenska vid Glosbe, online-lexikon, gratis. Bläddra milions ord och fraser på alla språk
  3. istration induces a cystic fibrosis-specific hepatobiliary phenotype, including changes in bile composition. These changes could not be associated with CFLD like pathological changes in CF mouse livers. However, Cholic acid cholate ad
  4. Visit ChemicalBook To find more Cholic acid(81-25-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. You can also browse global suppliers,vendor,prices,Price,manufacturers of Cholic acid(81-25-4). At last,Cholic acid(81-25-4) safety, risk, hazard and MSDS, CAS,cas.

Cholic acid and the fluorinated bile acid analogues caused a dose-dependent decrease in the uptake of [[sup.3]H]TC and [[sup.3]H]EbG for NTCP and OATP1B1. Evaluating Hepatobiliary Transport with [sup.18]F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performanc CHOLBAM ® (cholic acid) capsules is a medicine that can help these conditions.. CHOLBAM ® is a bile acid indicated for: . Treatment of bile acid synthesis disorders due to single enzyme defects; Adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who show signs and symptoms of liver disease, steatorrhea (fatty stools), or complications from. Cholic acid has no listed mild interactions with other drugs. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist Compound Cholic acid with free spectra: 4 NMR and 2 FTIR High-quality products creates a strong value. proposition for these products in the life science research communit

Cholic Acid - an overview ScienceDirect Topic

Cholic acid is a bile acid. Bile acids are produced naturally in the body to aid in digestion of fats and certain nutrients. People with bile acid disorders are unable to produce cholic acid normally. This can make it harder for the body to absorb nutrients important for health, growth, and body functioning. Abnormal.. Cholic acid feeding leads to increased CYP2D6 expression in CYP2D6-humanized mice. As a cholestasis model, Tg-CYP2D6 mice are fed a Cholic acid (CA)-supplemented diet for over 1 week.The treatment is known to increase bile acid pool size by 2-fold and to replace ~90% of bile acids with CA, recapitulating the features of cholestatic conditions in humans Cholic acid definition is - a crystalline bile acid C24H40O5 Chemsrc provides cholic acid(CAS#:81-25-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of cholic acid are included as well Information for Cholic acid [C 24 H 40 O 5 ] 81-25-4 including Cholic acid [C 24 H 40 O 5 ] CAS NO 81-25-4, Cholic acid [C 24 H 40 O 5 ] Suppliers, Cholic acid [C 24 H 40 O 5 ] Manufacturers, related products of Cholic acid [C 24 H<sub>40</sub>O<sub>5</sub>]

Cholic acid is a bile acid. Bile acids are produced naturally in the body to aid in digestion of fats and certain nutrients. People with bile acid disorders are unable to produce cholic acid normally Cholic-Acid-Derived Amphiphiles Can Prevent and Degrade Fungal Biofilms Ragini Gupta Laboratory of Nanotechnology and Chemical Biology, Regional Centre for Biotechnology, Third Milestone Faridabad-Gurgaon Expressway, NCR Biotech Science Cluster, Faridabad 121001, Haryana, Indi cholic: ( kō'lik ), Relating to the bile. Synonym(s): cholei 571 cholic acid products are offered for sale by suppliers on Alibaba.com A wide variety of cholic acid options are available to you, such as medicine grade. There are 29 suppliers who sells cholic acid on Alibaba.com, mainly located in Asia Bioequivalence, generics, cholic acid: Description: This document provides product-specific guidance on the demonstration of the bioequivalence of cholic acid capsules 50 mg and 250 mg. Abbreviations: BCS Classification: Biopharmaceutics Classification Syste

To investigate the effects of abolished cholic acid (CA) synthesis in the ApoE knockout model [apolipoprotein E (apoE) KO],a double-knockout (DKO) mouse model was created by crossbreeding Cyp8b1 knockout mice (Cyp8b1 KO), unable to synthesize the primary bile acid CA, with apoE KO mice. After 5 months of cholesterol feeding, the development of atherosclerotic plaques in the proximal aorta was. cholic acid: ChEBI ID CHEBI:16359: Definition A bile acid that is 5β-cholan-24-oic acid bearing three α-hydroxy substituents at position 3, 7 and 12. Stars This entity has been manually annotated by the ChEBI Team

Oral Cholic Acid in Zellweger Spectrum Disorders: A Word of Caution. Oral Cholic Acid in Zellweger Spectrum Disorders: A Word of Caution J Pediatr Gastroenterol Nutr. 2018 Feb;66(2):e57. doi: 10.1097/MPG.0000000000001763. Authors. Cholic Acid - Last updated on July 5, 2020 ©2020 Memorial Sloan Kettering Cancer Center. Educational Resources. Log in to print or send this list to your patient and save lists of resources you use frequently. Add resources to your list by clicking the checkbox next to the title cholic acid acid bile alcohol material Prior art date 1951-07-23 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Expired - Lifetime Application number US238195A Inventor Harold G Baker Stephen M Creighto cas: 81-25-4 einecs: 201-337- cholic acid. Molecular Formula C 24 H 40 O 5; Average mass 408.571 Da; Monoisotopic mass 408.287567 Da; ChemSpider ID 192176 - 11 of 11 defined stereocentres. More details: Systematic name (3alpha,5beta,7alpha,12alpha)-3,7,12-Tri hydroxycholan-24-oic acid. SMILES

Cholic Acid - Karolinska Institute

ApplicationNon-denaturing ionic detergent used for extraction of membrane proteins. ActionsBile AcidPackaging1 kg in poly bottle25,100,500 g in poly bottl Listade är 26 internationella och pålitliga leverantörer för Cholic acid. De kommer från 7 länder runt om i världen. Dessa leverantörer hör till 6 olika typer av företag som 'Bulk and laboratory supplier' och 'Producer

Cholic acid FGK is a medicine that contains the active substance cholic acid. Ácido cólico FGK es un medicamento cuyo principio activo es el ácido cólico . Cholic acid FGK is used for the life-long treatment of adults and children from one month of age who cannot produce enough primary bile acids such as cholic acid due to genetic abnormalities that result in a lack of liver enzymes Define cholic acid. cholic acid synonyms, cholic acid pronunciation, cholic acid translation, English dictionary definition of cholic acid. n. An abundant crystalline bile acid, C24H40O5, derived from cholesterol. n a crystalline insoluble acid present in bile:. Cholic acid definition: crystalline acid found in bile | Meaning, pronunciation, translations and example

Cholic acid is a non-denaturing ionic detergent used for extraction of membrane proteins China Cholic Acid manufacturers - Select 2020 high quality Cholic Acid products in best price from certified Chinese Pharmaceutical Intermediates manufacturers, China Cholesterol suppliers, wholesalers and factory on Made-in-China.co

Cholic acid definition of cholic acid by Medical dictionar

View All Manufacturers & Suppliers of Cholic Acid API with Drug Master Files (DMF), CEP/COS, Japanese DMFs, Written Confirmation (WC) details listed on PharmaCompass.co Cholic acid is a primary bile acid synthesized from cholesterol in the liver. In bile acid synthesis disorders due to SEDs in the biosynthetic pathway and in PDs, including Zellweger spectrum disorders, deficiency of primary bile acids leads to unregulated accumulation of intermediate bile acids and cholestasis Cholic acid. Pharmaceutical form(s) Capsule, hard. Age-appropriate oral formulation. Condition(s) / indication(s) Treatment of other inborn errors of bile acid synthesis. Treatment of oxysterol 7a-hydrolylase deficiency and defective amida. Route(s) of administration. Cholic acid feeding led to significantly decreased levels of expression of oatp1 and oct1 and an increased level of expression of oatp2 in wild-type mouse liver. In FXR-null mice,. Cholic acid, along with chenodeoxycholic acid, is one of two major bile acids produced by the liver where it is synthesized from cholesterol. Of the two major bile acids, cholate derivatives represent approximately eighty percent of all bile acids

CHOLIC ACID Prepared at the 17th JECFA (1973), published in FNP 4 (1978) and in FNP 52 (1992). Metals and arsenic specifications revised at the 55th JECFA (2000). An ADI of 0-1.25 mg/kg bw was established at the 17th JECFA (1973) SYNONYMS INS No. 1000 DEFINITIO Cholic acid is a naturally occurring detergent and belongs to the group of bile acids, which function as emulsifier of neutral lipids in the mammalian digestion tract. It is synthesized in the liver from cholesterol. After further derivatization to glycocholic and taurocholic acid, it is secreted into the bile Cholic acid is a bile acid, [1] a white crystalline substance insoluble in water (soluble in alcohol and acetic acid), with a melting point of 200-201 °C.Salts of cholic acid are called cholates.Cholic acid, along with chenodeoxycholic acid, is one of two major bile acids produced by the liver where it is synthesized from cholesterol.Of the two major bile acids, cholate derivatives represent. Global cholic Acid markedsundersøkelsesrapport 2020-2026 er en historisk oversikt og grundig studie av det nåværende og fremtidige markedet for cholic Acid-industrien. Rapporten representerer en grunnleggende oversikt over cholic Acids markedsandel, konkurrentesegment med en grunnleggende introduksjon av nøkkelleverandører, toppregioner, produkttyper og sluttindustri

Cholic acid bovine and/or ovine, >= 98 % 81-25-4 Sigma

Compare prices and print coupons for Cholic Acid (Cholbam) and other Bile Acid Synthesis Disorder drugs at CVS, Walgreens, and other pharmacies. Prices start at $8,170.8 For instance a blue molecular compd (C 24 H 40 O 5 I) 4.KI.H 2 O, may be prepd by mixing an alcoholic soln of cholic acid and a soln of iodine in aq potassium iodide: Barger, Field, J. Chem. Soc. 101, 1404 (1912)

Cholic Acid Home / Products / Bile Acids / Primary Bile Acids / Cholic Acid. Cholic Acid Unlabeled Size. 50mg $ 55.00. Quantity. Add To Cart. Request Bulk and Custom Quantities Catalog # 13098UNL: CAS # 81-25-4. Labeled: Unlabeled. Purity ≥98%. Safety: Non-Hazardous. Related Categories. Bile Acid Sulfates; Glucuronides Cholic acid (Cholbam) is considered experimental, investigational or unproven for any other use including the following: • Extrahepatic manifestations of bile acid synthesis disorders due to single enzyme defects or peroxisomal disorders, including Zellweger spectrum disorders Cholic acid is a primary bile acid synthesized from cholesterol in the liver. Endogenous bile acids including cholic acid enhance bile flow and provide the physiologic feedback inhibition of bile acid synthesis. The mechanism of action of cholic acid has not been fully established;.

Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. (wikipedia.org) This is why chenodeoxycholic acid, and not cholic acid, can be used to treat gallstones (because decreasing bile acid synthesis would supersaturat A family of steroids comprising the bile acids (or salts), generally in conjugated form ( e.g., glycocholic and taurocholic acid s). Chemically, cholic acid s are cholan 24 oic (cholanic) acids (the terminal C24 of cholane becoming a COOH group)

Ursodeoxy cholic acid Sigma-Aldric

  1. Ischemic stroke (IS) can disrupt various types of brain cells in the neurovascular unit (NVU) at both the structural and functional levels. Therefore, NVU is considered to be a more comprehensive target for the treatment of IS. It is necessary to develop drugs which targeted multiple mechanisms and cell types on NVU against IS. As a component of bile acid, cholic acid has been reported to be.
  2. Preparation of crude cholic acid of cattle, sheep: take bovine or sheep bile; add 100 g/L sodium hydroxide; heat to boil for 12-18h to get saponification solution. Cooling. Adding acid to pH 1, precipitating cholic acid, removing bile acid, undergoing boiling and rinsing, drying at 75℃, milling can obtain bovine cholic acid
  3. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine to form bile salts. 1 Cholic acid facilitates fat absorption and cholesterol excretion. 2,3 WARNING This product is not for human or veterinary use
  4. Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the t

Cholic Acid, Sodium Salt sc-280641 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Cholic Acid, Sodium Salt STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA SUPPLIE cholic acid cbd was clearly for the Problem developed, . The Use is either About a short period or longer - depending on the wanted Results & the different individual Strengths of action. Friends beaming User talk About your beautiful Achievements with cholic acid cbd Cholic acid: Description: Cholic acid is a major primary bile acid produced in the liver and is usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Bile acids are steroid acids found predominantly in the bile of mammals

Glycine

Cholic acid - Bactoche

  1. Product Name Item Number Unit Chemical purity Linear formula Price (excl. VAT) Qty; CHOLIC ACID (24-13C, 99%) CLM-2710-.1: 0.1 G: 98% *CC23H40O
  2. Cholic patients Cholic acid C.B.D.. 13. Cholic acid small particles) fats and insoluble in water it at the head of Seed Oil and Its in rats with complete to emulsify (breakdown into of bile acid synthesis internal standard (IS), and acetic acid were cholic acid and a acid concentrations obtained b
  3. Entries with cholic cholic acid: cholic acid (English) Origin & history Mid 19th century, from Greek kholikos, from kholē (bile).Noun cholic acid (uncountable) biochemistry - a steroidal bile acid, C24H40O5, derived. lithocholic: lithocholic (English) Origin & history From litho- + cholic Adjective lithocholic (not comparable) Of or pertaining to lithocholic acid
Diabetes and Dyslipidemia: Interrelationships and Clinical

I am doing an experiment and I need to induce hypercholesterolemia in rats. I am using cholic acid (0.5% of their food ratio) and cholesterol powder (2% of their food ratio) Side Effects. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention Cholic acid is obtained naturally from ox bile extracts and commercially from cholesterol. It is used as a natural sequestrant and detergent. Bile acid can neutralize pH and solubilize many inorganic salts. The sodium salt of cholic acid is the primary component in oxgall Cholic acid is a primary bile acid that is synthesized from excess cholesterol by the liver. Bile acid synthesis is critical for cholesterol removal from the body and uptake of dietary lipids, fat soluble vitamins, and other nutrients from the small intestine. Determining circulatory levels of bile acids can be used to identify certain liver diseases

Cancers | Free Full-Text | Muscarinic Receptor Signaling

Cholic acid VW

  1. Media in category Cholic acid The following 11 files are in this category, out of 11 total
  2. functionalized cholic acid scaffold resulted in compounds with moderate antimicrobial activity, which prompted us to synthesize additional cholic acid−lysine-based cationic amphi-philes. Accordingly, the intermediate 9 was coupled with Fmoc−Lys(Boc)−OH to yield a fully protected dipeptide 12 (Scheme 2)
  3. Ceragenins: cholic acid-based mimics of antimicrobial peptides Acc Chem Res. 2008 Oct;41(10):1233-40. doi: 10.1021/ar700270t. Epub 2008 Jul 11. Authors Xin-Zhong Lai 1 , Yanshu Feng, Jacob Pollard, Judy N Chin, Michael J Rybak, Robert Bucki, Raquel F Epand, Richard M Epand, Paul B Savage. Affiliation 1 Department of.
  4. absorption
  5. Find patient medical information for Cholic Acid Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings

Cholic acid is a primary bile acid synthesized from cholesterol in the liver. In bile acid synthesis disorders due to SEDs in the biosynthetic pathway, and in PDs including Zellweger spectrum disorders, deficiency of primary bile acids leads to unregulated accumulation of intermediate bile acids and cholestasis Cholic Chol ic, Cholinic Cho*lin ic, a. [Gr. ?, from ? bile.] (Physiol. Chem.) Pertaining to, or obtained from, the bile. [1913 Webster] {Cholic acid} (Chem.), a complex organic acid found as a natural constituent of taurocholic and glycocholi Ser., 1966, 339 2 Tenth Report of the Joint FAO/WHO Expert Committee on Food Additives, FAO Nutrition Meetings Report Series, 1967, in press; Food and Agriculture Organization of the United Nations World Health Organization 1967 CHOLIC ACID Chemical name 3,7,12-trihydroxycholanic acid Empirical formula C 24 H 40 O 5 Structural formula Molecular weight 408.58 Definition Cholic acid after drying.

Cholic acid is indicated for the treatment of bile acid synthesis disorders due to single enzyme defects (SED), and as adjunctive treatment of peroxisomal disorder (PD), including Zellweger spectrum disorder in patients who exhibit manifestation of liver disease, steatorrhea, or complications from decreased fat-soluble vitamin absorption. CHOLIC AND DESOXYCHOLIC ACID AND THEIR SALTS Explanation These substances were evaluated for acceptable daily intake by the Joint FAO/WHO Expert Committee on Food Additives (see Annex 1, Ref. No. 13) in 1966. Since the previous evaluation, additional data have. NHS England will commission cholic acid and chenodeoxycholic acid for treating inborn errors of bile acid synthesis for all age groups in accordance with the criteria outlined in this document

Cholic Acid, Sodium Salt - CAS 361-09-1 - Calbiochem CAS 361-09-1 Primary bile acid. - Find MSDS or SDS, a COA, data sheets and more information Cholic acid, a primary bile acid, enhances bile flow and provides the physiologic feedback inhibition of bile acid synthesis to maintain bile acid homeostasis. Indication : • Bile acid synthesis disorders • Peroxisomal disorders. Contraindications : No contraindications. Dosing : Ora Swedish Translation for cholic acid - dict.cc English-Swedish Dictionar Simagchem Corporation is supplier for Cholic acid. Expertize in supplies and sources of fine, specialty, pharmaceutical chemicals and intermediates. WE offer high quality products and JIT services with instant market intelligence in China, custom synthesis in our 3 production sites, famous principals as Brenntag, Univar,S inopec, Grace. Synonyms for cholic acid in Free Thesaurus. Antonyms for cholic acid. 1 word related to cholic acid: bile acid. What are synonyms for cholic acid

MECHANISMS IN ENDOCRINOLOGY: Bile acid sequestrants inExcretion Cartoons, Illustrations & Vector Stock ImagesLiposomal Nanomedicine for Breast Cancer TherapyMalabsorption syndrome ppt

CHOLBAM ® (cholic acid) capsules may help patients with bile acid synthesis disorders due to single enzyme defects and patients with liver involvement in Zellweger spectrum disorders . CHOLBAM is the FIRST and ONLY FDA-APPROVED treatment indicated for CHOLBAM ® is indicated for:. Treatment of bile acid synthesis disorders due to single enzyme defect Metal cholates preparation in aqueous solvent: cholic acid was dissolved in aqueous sodium hydroxide solution, then treated with one equivalent of aqueous metal salt solution. Cholic acid (IUPAC name 3[alpha],7[alpha],12[alpha]-trihydroxy-5[beta]-cholan-24-oic acid) is a bile acid [15], is a white crystalline water insoluble substance (soluble in alcohol and acetic and acid), and its salts. cholic acid definition: an acid, CHO, found in the bile, generally in combination with amino acidsOrigin of cholic acidfrom Classical Greek cholikos from chol?, bile: see cholera.. Cholic Acid (2 g) Catalog # 1133503: Current Lot R07280: Previous Lot R016D0 (Valid Use Date: 30-JUN-2018) SDS View: USP Certificate for Current Lot View: CAS# 81-25-4: In Stock Yes: Available for Shipping Yes: Origin Information View: USP Certificates and. Cholic acid is used as a preservative for food. It is widely used as an intermediate in the manufacture of pharmaceuticals. It finds use in biological research. It helps in detergents to soften biological fats. It helps in preventing and melting gallstones

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